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EU Panel Likes Azacitidine for AML Repairs

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The Committee for Medicinal Merchandise for Human Exhaust (CHMP) of the European Medicines Company (EMA) adopted a clear notion of azacitidine (Onureg) for use as repairs remedy in patients with acute myeloid leukemia (AML) who grasp carried out a first total remission. The advice for advertising and marketing authorization additionally involves use in patients who grasp carried out total remission with incomplete blood count recovery after induction chemotherapy (with or with out consolidation medication) and who are unable to proceed to hematopoietic stem cell transplantation. Azacitidine can be readily accessible as 200-mg and 300-mg movie-coated pills. The drug exerts its antineoplastic results by multiple mechanisms, including cytotoxicity on cells with...